There was also a huge increase in the number of cases, with 14,840 people diagnosed with Covid-19.
Hubei has started using a broader definition to diagnose people – which accounts for most of the rise in cases.
China sacked two top officials in Hubei province hours after the new figures were revealed.
Until Wednesday’s increases, the number of people with the virus in Hubei, where the outbreak emerged, was stabilising.
But the new cases and deaths in the province have pushed the national death toll above 1,350 – with almost 60,000 infections in total.